I know exactly what you mean.
When Lisa began commenting on my weight, I recognized immediately her dissatisfaction with her own life because it started right around the time that she was lost her job at the bank.
I know that she was feeling down and vulnerable, so I was forgiving, but I really wanted to smack her. Really. I was angry about it later, and hurt. I hadn't said a thing after she and Dave broke up for the (what?) 15th time and you know that I really wanted to, but I kept my mouth shut because I knew it would be hurtful to her. I wish she'd had the same respect for me.
Probably the most hurtful thing was that I had just told her that I would be ready to work on the outside when I was done working on the inside.
There's a lot of stress in your life right now, so go easy on yourself.
I'm sorry you're feeling so down.